Critical Path Institute

Tucson, AZ · EIN 20-1991334 · 501(c)(3) · Publicly supported organization (170(b)(1)(A)(vi))
Latest filing: Form 990 for the fiscal year ending June 30, 2025 (tax year 2024) · View the filing · Correct or respond

Critical Path Institute reported $46.8 million in revenue and $40.2 million in expenses for the fiscal year ending June 30, 2025. Of every $100 it spent, $77.93 went to program services, $22.07 to management and general costs and $0.00 to fundraising. Its largest source of revenue was contributions and grants: 71.7% of the total. Government grants made up 44.3%. The highest compensation it reported for one person was $519,080 (CEO). 81 people received more than $100,000 in reportable compensation. Revenue rose 153% between FY2020 and FY2025. Source: Form 990, FY2025.

Where $100 of spending went

The fiscal year ending June 30, 2025 · Form 990, Part IX, line 25 · total expenses $40M

Program services$77.93 $31M
Management & general$22.07 $8.9M
Fundraising$0.00 $0

For context, the median across 169 covered medical research charities: $87.02 programs, $12.87 management, $0.11 fundraising (medians computed separately, so they may not sum to $100).

Where $100 of revenue came from

The fiscal year ending June 30, 2025 · Form 990, Part VIII · total revenue $47M

Contributions & grants (non-government)$27.44 $13M
Government grants$44.30 $21M
Program service revenue$26.26 $12M
Investment income$2.00 $935K

The 990 scorecard · same measures for every charity, no grades

FY2025 filing. Median across 169 covered charities in this category, from their latest filings.
Measure	FY2025	Median
Program services Part IX 25(B) ÷ 25(A)	77.9%	83.9%
Management & general Part IX 25(C) ÷ 25(A)	22.1%	12.4%
Fundraising Part IX 25(D) ÷ 25(A)	0.0%	0.1%
Fundraising cost per $1 of contributions Part IX 25(D) ÷ Part VIII 1h	$0.00	$0.01
Contributions & grants share of revenue Part VIII 1h ÷ 12	71.7%	72.7%
Government grants share of revenue Part VIII 1e ÷ 12	44.3%	0.0%
Program service revenue share Part VIII 2g ÷ 12	26.3%	5.8%
Highest reported compensation Part VII-A, columns D–F	$519,080	$628,890
Highest compensation as share of expenses Part VII-A ÷ Part IX 25(A)	1.29%	1.94%
People paid over $100,000 Part VII, line 2	81	18
Net assets, in months of expenses Part X 33(B) ÷ monthly expenses	7.8	13.3
Independent voting board members Part VI 1a–1b	16 of 16	93.8%

A median is context, not a target: hospitals, universities, food banks and grantmakers spend in very different ways. What these measures can and can't tell you.

What the money paid for, in its own words

FY2025 · Form 990, Part III · the three largest programs by expense

$6.7M expenses · 21.4% of program spending

Critical Path for rare neurodegenerative diseases (cp-rnd)

$6.1M expenses · 19.3% of program spending · grants $1.3M

Rare disease cures accelerator-data and analytics platform (rdca-dap)

$2.9M expenses · 9.2% of program spending · grants $1.6M

Critical Path Institute's translational therapeutics accelerator (trxa)

$16M all other programs (line 4d)

Highest reported compensation

FY2025 · Form 990, Part VII, Section A · roles as filed; names are in the filing, not here

Role	From this org	From related orgs	Other	Total
CEO Officer, 40.00 hrs/week	$465,393	$0	$53,687	$519,080
PRESIDENT & COO Officer, 40.00 hrs/week	$382,404	$0	$57,742	$440,146
VP PROGRAMS Key employee, 40.00 hrs/week	$322,075	$0	$42,056	$364,131
CHIEF FINANCIAL OFFICER & TREASURER Officer, 40.00 hrs/week	$279,156	$0	$45,481	$324,637
CHIEF TECHNOLOGY OFFICER Key employee, 40.00 hrs/week	$267,416	$0	$38,055	$305,471
EXECUTIVE DIRECTOR Highest compensated employee, 40.00 hrs/week	$260,883	$0	$36,587	$297,470
EXECUTIVE DIRECTOR Highest compensated employee, 40.00 hrs/week	$257,993	$0	$38,055	$296,048
VP PROGRAMS Key employee, 40.00 hrs/week	$273,459	$0	$22,337	$295,796

81 people received more than $100,000 in reportable compensation from Critical Path Institute (Part VII, line 2). Compensation of current officers, directors and key employees totaled $2.3M (Part IX, line 5).

6 years of filings

Form 990, Parts I, VII, IX and X · each row is that year's own filing, linked

RevenueExpenses

Filing	Revenue	Expenses	Programs	Net assets	Top pay
FY2025 ⓘ	$47M	$40M	77.9%	$26M	$519,080
FY2024 ⓘ	$43M	$38M	80.5%	$20M	$459,407
FY2023 ⓘ	$35M	$32M	81.9%	$15M	$356,465
FY2022 ⓘ	$31M	$30M	85.1%	$12M	$346,727
FY2021 ⓘ	$24M	$23M	72.5%	$10M	$396,202
FY2020 ⓘ	$18M	$18M	76.5%	$9.0M	$260,441

Governance answers, as filed

FY2025 · the organization's own yes/no answers; explanations, if any, are in Schedule O of the filing · what each means

Voting board members, and how many are independent Part VI, lines 1a–1b16 · 16 independent
Audited financial statements Part XII 2bYes
Conflict-of-interest policy Part VI 12aYes
Whistleblower policy Part VI 13Yes
Document retention policy Part VI 14Yes
Independent process for top executive pay Part VI 15aYes
Board given the 990 before filing Part VI 11aYes
Family or business ties among insiders Part VI 2Yes
Aware of a significant diversion of assets Part VI 5No
Excess benefit transaction with an insider Part IV 25aNo
Loans to or from insiders outstanding Part IV 26No
Lobbying, or a 501(h) election in effect Part IV 4Yes
Over $15,000 of professional fundraising services Part IV 18No
Over $10,000 of activity outside the U.S. Part IV 14bYes
Employees Part I, line 5176
Volunteers Part I, line 616

Largest outside contractors

FY2025 · Form 990, Part VII, Section B · businesses only

ARIDHIA INFORMATICS LIMITED It services	$1,420,719
AMAZON WEB SERVICES INC It services	$436,866
LOTOS NILE Public relations	$384,258
TRIPLE POINTE HOLDINGS LLC Consulting	$247,458
ROCHE DIAGNOSTICS OPERATIONS INC Research support	$245,000

Individuals listed as contractors are left out. 11 contractors were paid more than $100,000 in all.

Private foundation grants it received

3 private foundations reported grants to Critical Path Institute totaling $557K on their tax year 2023 Form 990-PF returns. See which foundations, on WHOFUNDS.

Source: WHOFUNDS open grant graph, matched from Form 990-PF Part XV.

Correct a figure or respond

Every number above is copied from Critical Path Institute's own Form 990. If one doesn't match the filing, that's our error and we'll fix it. If you work for Critical Path Institute, you can publish a response that is linked from this page.

Report a correction Respond as Critical Path Institute How this works

Similar-sized charities in this cause

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Huntsman Cancer Foundation
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Nsabp Foundation
Pittsburgh, PA · revenue $44M · programs 98.8% · FY2025

All medical research charities · Largest charities in Arizona

Questions people ask

How much of Critical Path Institute's spending goes to programs?

In the fiscal year ending June 30, 2025, Critical Path Institute reported that 77.9% of its $40.2 million in expenses went to program services, 22.1% to management and general and 0.0% to fundraising (Form 990, Part IX).

How much does Critical Path Institute pay its top executive?

The largest total compensation Critical Path Institute reported for one person in the fiscal year ending June 30, 2025 was $519,080, for the role of CEO (Form 990, Part VII, including compensation from related organizations and other compensation).

Where does Critical Path Institute get its money?

Of $46.8 million in revenue in the fiscal year ending June 30, 2025, 71.7% came from contributions and grants (including 44.3% from government grants) and 26.3% from program service revenue (Form 990, Part VIII).

Is Critical Path Institute a registered charity?

The IRS lists EIN 20-1991334 as a 501(c)(3) organization (publicly supported organization (170(b)(1)(a)(vi))), and its records show contributions as tax-deductible. Form 990 filings on record here cover tax years 2019, 2020, 2021, 2022, 2023, 2024. A filing shows what the organization reported; it doesn't by itself show whether a program works.

Sources

FY2025: Form 990 for the fiscal year ending June 30, 2025, object 202620619349300337 · read the filing · XML
FY2024: Form 990 for the fiscal year ending June 30, 2024, object 202531009349300938 · read the filing
FY2023: Form 990 for the fiscal year ending June 30, 2023, object 202410809349300526 · read the filing
FY2022: Form 990 for the fiscal year ending June 30, 2022, object 202330979349300518 · read the filing
FY2021: Form 990 for the fiscal year ending June 30, 2021, object 202240809349300989 · read the filing
FY2020: Form 990 for the fiscal year ending June 30, 2020, object 202111279349303111 · read the filing

All filings for EIN 20-1991334: ProPublica Nonprofit Explorer · IRS Tax Exempt Organization Search. Figures are as the organization reported them; we have not audited them.