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Global Coalition for Adaptive Research

Larkspur, CA · EIN 82-1199380 · 501(c)(3) · Publicly supported organization (170(b)(1)(A)(vi))
Latest filing: Form 990 for calendar year 2025 (tax year 2025) · View the filing · Correct or respond

Global Coalition for Adaptive Research reported $32.4 million in revenue and $32.6 million in expenses for calendar year 2025. Of every $100 it spent, $91.72 went to program services, $8.28 to management and general costs and $0.00 to fundraising. Its largest source of revenue was program service revenue such as fees, sales and contracts: 91.0% of the total. The highest compensation it reported for one person was $1,321,615 (CHIEF EXECUTIVE OFFICER/PRESIDENT). 26 people received more than $100,000 in reportable compensation. Revenue rose 172% between 2019 and 2025. Source: Form 990, 2025.

Where $100 of spending went

Calendar year 2025 · Form 990, Part IX, line 25 · total expenses $33M

For context, the median across 169 covered medical research charities: $87.02 programs, $12.87 management, $0.11 fundraising (medians computed separately, so they may not sum to $100).

Where $100 of revenue came from

Calendar year 2025 · Form 990, Part VIII · total revenue $32M

The 990 scorecard · same measures for every charity, no grades

2025 filing. Median across 169 covered charities in this category, from their latest filings.
Measure2025Median
Program services
Part IX 25(B) ÷ 25(A)
91.7%83.9%
Management & general
Part IX 25(C) ÷ 25(A)
8.3%12.4%
Fundraising
Part IX 25(D) ÷ 25(A)
0.0%0.1%
Fundraising cost per $1 of contributions
Part IX 25(D) ÷ Part VIII 1h
$0.00$0.01
Contributions & grants share of revenue
Part VIII 1h ÷ 12
3.2%72.7%
Government grants share of revenue
Part VIII 1e ÷ 12
0.0%0.0%
Program service revenue share
Part VIII 2g ÷ 12
91.0%5.8%
Highest reported compensation
Part VII-A, columns D–F
$1,321,615$628,890
Highest compensation as share of expenses
Part VII-A ÷ Part IX 25(A)
4.05%1.94%
People paid over $100,000
Part VII, line 2
2618
Net assets, in months of expenses
Part X 33(B) ÷ monthly expenses
16.313.3
Independent voting board members
Part VI 1a–1b
5 of 893.8%

A median is context, not a target: hospitals, universities, food banks and grantmakers spend in very different ways. What these measures can and can't tell you.

What the money paid for, in its own words

2025 · Form 990, Part III · the three largest programs by expense
$27M expenses · 91.8% of program spending · grants $19,670 · revenue $27M

Gbm agile (glioblastoma Adaptive Global innovative learning environment) is uniquely designed as a long-standing platform with the ability to test multiple therapies at the same time against a common control (or standard of care). The purpose is to evaluate multiple investigational treatments for either newly diagnosed or recurrent glioblastoma to determine if any of these study treatment(s) improve overall survival as compared to standard treatments

$2.5M expenses · 8.2% of program spending · revenue $2.9M

Other ongoing programs or programs in development gcar serves as the regulatory sponsorship of the military and veterans ptsd adaptive platform clinical trial (m-pact). Partnering with operational medical systems, part of the defense health agency, gcar is conducting an adaptive platform trial at is evaluating multiple pharmacotherapeutic interventions for the treatment of ptsd for active-duty service members and veterans with ptsd at multiple clinical sites in the US. This program is supported by a project team that also includes representatives from the U.S. Air force, army, navy, and…

Highest reported compensation

2025 · Form 990, Part VII, Section A · roles as filed; names are in the filing, not here
RoleFrom this orgFrom related orgsOtherTotal
CHIEF EXECUTIVE OFFICER/PRESIDENT
Officer, 40.00 hrs/week
$1,269,450$0$52,165$1,321,615
CHIEF BUSINESS AND STRATEGY OFFICER
Key employee, 40.00 hrs/week
$812,461$0$15,200$827,661
CFO/COO/TREASURER
Officer, 40.00 hrs/week
$541,250$0$31,098$572,348
VICE PRESIDENT, TRIAL OPERATIONS
Key employee, 40.00 hrs/week
$520,625$0$13,882$534,507
COMMUNITY ENGAGEMENT/TRAINING LEAD
Highest compensated employee, 40.00 hrs/week
$266,440$0$19,558$285,998
DIRECTOR, QUALITY AND NEW INITIATIVES
Highest compensated employee, 40.00 hrs/week
$255,150$0$30,075$285,225
DIRECTOR, LEGAL/SECRETARY
Officer, 40.00 hrs/week
$245,350$0$31,244$276,594
DIRECTOR, TRIAL OPERATIONS
Highest compensated employee, 40.00 hrs/week
$246,909$0$29,119$276,028

26 people received more than $100,000 in reportable compensation from Global Coalition for Adaptive Research (Part VII, line 2). Compensation of current officers, directors and key employees totaled $3.8M (Part IX, line 5).

7 years of filings

Form 990, Parts I, VII, IX and X · each row is that year's own filing, linked
RevenueExpenses
$0$10M$20M$30M$40M2019202020212022202320242025$32M$33M
FilingRevenueExpensesProgramsNet assetsTop pay
2025 ⓘ$32M$33M91.7%$44M$1,321,615
2024 ⓘ$28M$31M86.7%$39M$1,004,529
2023 ⓘ$29M$30M91.3%$40M$898,687
2022 ⓘ$35M$24M95.5%$38M$748,256
2021 ⓘ$39M$19M97.1%$27M$569,393
2020 ⓘ$16M$10M94.1%$5.3M$459,412
2019 ⓘ$12M$5.2M81.9%$6.6M$307,500

Governance answers, as filed

2025 · the organization's own yes/no answers; explanations, if any, are in Schedule O of the filing · what each means
  • Voting board members, and how many are independent Part VI, lines 1a–1b8 · 5 independent
  • Audited financial statements Part XII 2bYes
  • Conflict-of-interest policy Part VI 12aYes
  • Whistleblower policy Part VI 13Yes
  • Document retention policy Part VI 14Yes
  • Independent process for top executive pay Part VI 15aYes
  • Board given the 990 before filing Part VI 11aYes
  • Family or business ties among insiders Part VI 2No
  • Aware of a significant diversion of assets Part VI 5No
  • Excess benefit transaction with an insider Part IV 25aNo
  • Loans to or from insiders outstanding Part IV 26No
  • Lobbying, or a 501(h) election in effect Part IV 4No
  • Over $15,000 of professional fundraising services Part IV 18No
  • Over $10,000 of activity outside the U.S. Part IV 14bNo
  • Employees Part I, line 540
  • Volunteers Part I, line 65

Largest outside contractors

2025 · Form 990, Part VII, Section B · businesses only
IQVIA
Cro services
$14,683,453
MEDIDATA
Data services
$441,610
BERRY CONSULTANTS LLC
Statistical consultation
$275,720
MEDQIA
Data services
$189,335

Individuals listed as contractors are left out. 5 contractors were paid more than $100,000 in all.

Private foundation grants it received

2 private foundations reported grants to Global Coalition for Adaptive Research totaling $2,074 on their tax year 2023 Form 990-PF returns. See which foundations, on WHOFUNDS.

Source: WHOFUNDS open grant graph, matched from Form 990-PF Part XV.

Correct a figure or respond

Every number above is copied from Global Coalition for Adaptive Research's own Form 990. If one doesn't match the filing, that's our error and we'll fix it. If you work for Global Coalition for Adaptive Research, you can publish a response that is linked from this page.

Similar-sized charities in this cause

All medical research charities · Largest charities in California

Questions people ask

How much of Global Coalition for Adaptive Research's spending goes to programs?

In calendar year 2025, Global Coalition for Adaptive Research reported that 91.7% of its $32.6 million in expenses went to program services, 8.3% to management and general and 0.0% to fundraising (Form 990, Part IX).

How much does Global Coalition for Adaptive Research pay its top executive?

The largest total compensation Global Coalition for Adaptive Research reported for one person in calendar year 2025 was $1,321,615, for the role of CHIEF EXECUTIVE OFFICER/PRESIDENT (Form 990, Part VII, including compensation from related organizations and other compensation).

Where does Global Coalition for Adaptive Research get its money?

Of $32.4 million in revenue in calendar year 2025, 3.2% came from contributions and grants and 91.0% from program service revenue (Form 990, Part VIII).

Is Global Coalition for Adaptive Research a registered charity?

The IRS lists EIN 82-1199380 as a 501(c)(3) organization (publicly supported organization (170(b)(1)(a)(vi))), and its records show contributions as tax-deductible. Form 990 filings on record here cover tax years 2019, 2020, 2021, 2022, 2023, 2024, 2025. A filing shows what the organization reported; it doesn't by itself show whether a program works.

Sources

  • 2025: Form 990 for calendar year 2025, object 202601599349301135 · read the filing · XML
  • 2024: Form 990 for calendar year 2024, object 202531339349309023 · read the filing
  • 2023: Form 990 for calendar year 2023, object 202431169349302303 · read the filing
  • 2022: Form 990 for calendar year 2022, object 202301359349308010 · read the filing
  • 2021: Form 990 for calendar year 2021, object 202202569349301375 · read the filing
  • 2020: Form 990 for calendar year 2020, object 202113199349319446 · read the filing
  • 2019: Form 990 for calendar year 2019, object 202043189349306889 · read the filing

All filings for EIN 82-1199380: ProPublica Nonprofit Explorer · IRS Tax Exempt Organization Search. Figures are as the organization reported them; we have not audited them.