Institute for Systems Biology
Institute for Systems Biology reported $42.3 million in revenue and $47.6 million in expenses for calendar year 2024. Of every $100 it spent, $71.13 went to program services, $27.96 to management and general costs and $0.91 to fundraising. Its largest source of revenue was contributions and grants: 89.6% of the total. Government grants made up 55.3%. The highest compensation it reported for one person was $3,178,068 (DIRECTOR - THRU 3/24). 73 people received more than $100,000 in reportable compensation. Revenue rose 17% between 2019 and 2024. Source: Form 990, 2024.
Where $100 of spending went
Calendar year 2024 · Form 990, Part IX, line 25 · total expenses $48MFor context, the median across 192 covered science & technology charities: $84.33 programs, $15.67 management, $0.00 fundraising (medians computed separately, so they may not sum to $100).
Where $100 of revenue came from
Calendar year 2024 · Form 990, Part VIII · total revenue $42MThe 990 scorecard · same measures for every charity, no grades
| Measure | 2024 | Median |
|---|---|---|
| Program services Part IX 25(B) ÷ 25(A) | 71.1% | 83.2% |
| Management & general Part IX 25(C) ÷ 25(A) | 28.0% | 15.5% |
| Fundraising Part IX 25(D) ÷ 25(A) | 0.9% | 0.0% |
| Fundraising cost per $1 of contributions Part IX 25(D) ÷ Part VIII 1h | $0.01 | $0.00 |
| Contributions & grants share of revenue Part VIII 1h ÷ 12 | 89.6% | 51.6% |
| Government grants share of revenue Part VIII 1e ÷ 12 | 55.3% | 3.2% |
| Program service revenue share Part VIII 2g ÷ 12 | 1.9% | 19.2% |
| Highest reported compensation Part VII-A, columns D–F | $3,178,068 | $513,729 |
| Highest compensation as share of expenses Part VII-A ÷ Part IX 25(A) | 6.68% | 1.72% |
| People paid over $100,000 Part VII, line 2 | 73 | 27 |
| Net assets, in months of expenses Part X 33(B) ÷ monthly expenses | 14.9 | 14.7 |
| Independent voting board members Part VI 1a–1b | 12 of 16 | 94.3% |
A median is context, not a target: hospitals, universities, food banks and grantmakers spend in very different ways. What these measures can and can't tell you.
What the money paid for, in its own words
2024 · Form 990, Part III · the three largest programs by expenseSee schedule oat providence, we use our voice to advocate for vulnerable populations and needed reforms in health care. We are also pursuing innovative ways to transform health care by keeping people healthy, and making our services more convenient, accessible and affordable for all. In an increasingly uncertain world, we are committed to high-quality, compassionate health care for everyone - regardless of coverage or ability to pay. We help people and communities benefit from the best health care model for the future - today.together, our 125,000 caregivers (all employees) serve in 51…
Highest reported compensation
2024 · Form 990, Part VII, Section A · roles as filed; names are in the filing, not here| Role | From this org | From related orgs | Other | Total |
|---|---|---|---|---|
| DIRECTOR - THRU 3/24 Director/trustee, 0.50 hrs/week | $0 | $3,164,494 | $13,574 | $3,178,068 |
| DIRECTOR (PART YEAR) Director/trustee, 0.50 hrs/week | $0 | $2,675,264 | $22,605 | $2,697,869 |
| DIRECTOR Director/trustee, 0.50 hrs/week | $0 | $2,018,676 | $215,815 | $2,234,491 |
| DIRECTOR - THRU 6/24 Director/trustee, 0.50 hrs/week | $0 | $820,365 | $96,888 | $917,253 |
| PRESIDENT/PROFESSOR Officer, 55.00 hrs/week | $509,772 | $0 | $56,043 | $565,815 |
| SVP DIR OF INTEGRATIVE SCIENCE/PROF Officer, 55.00 hrs/week | $343,731 | $0 | $63,309 | $407,040 |
| COO/TREASURER Officer, 55.00 hrs/week | $323,595 | $0 | $61,124 | $384,719 |
| DIRECTOR OF DATA SCIENCE Highest compensated employee, 50.00 hrs/week | $282,804 | $0 | $43,781 | $326,585 |
73 people received more than $100,000 in reportable compensation from Institute for Systems Biology (Part VII, line 2). Compensation of current officers, directors and key employees totaled $1.6M (Part IX, line 5).
6 years of filings
Form 990, Parts I, VII, IX and X · each row is that year's own filing, linkedGovernance answers, as filed
2024 · the organization's own yes/no answers; explanations, if any, are in Schedule O of the filing · what each means- Voting board members, and how many are independent Part VI, lines 1a–1b16 · 12 independent
- Audited financial statements Part XII 2bYes
- Conflict-of-interest policy Part VI 12aYes
- Whistleblower policy Part VI 13Yes
- Document retention policy Part VI 14Yes
- Independent process for top executive pay Part VI 15aYes
- Board given the 990 before filing Part VI 11aYes
- Family or business ties among insiders Part VI 2Yes
- Aware of a significant diversion of assets Part VI 5No
- Excess benefit transaction with an insider Part IV 25aNo
- Loans to or from insiders outstanding Part IV 26No
- Lobbying, or a 501(h) election in effect Part IV 4No
- Over $15,000 of professional fundraising services Part IV 18No
- Over $10,000 of activity outside the U.S. Part IV 14bNo
- Employees Part I, line 5299
- Volunteers Part I, line 622
Largest outside contractors
2024 · Form 990, Part VII, Section B · businesses only| UNIVERSITY OF WASHINGTON Research grant subcontractor | $1,751,408 |
| SWEDISH HEALTH SERVICES Research grant subcontractor | $1,332,547 |
| BIOCENTRIQ INC Research grant subcontractor | $1,031,017 |
| SEATTLE CHILDRENS RESEARCH INSTITUTE Research grant subcontractor | $799,483 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA Research grant subcontractor | $720,890 |
Individuals listed as contractors are left out. 17 contractors were paid more than $100,000 in all.
Private foundation grants it received
5 private foundations reported grants to Institute for Systems Biology totaling $921K on their tax year 2023 Form 990-PF returns. See which foundations, on WHOFUNDS.
Source: WHOFUNDS open grant graph, matched from Form 990-PF Part XV.
Correct a figure or respond
Every number above is copied from Institute for Systems Biology's own Form 990. If one doesn't match the filing, that's our error and we'll fix it. If you work for Institute for Systems Biology, you can publish a response that is linked from this page.
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Of every $100 Institute for Systems Biology spent in 2024, $71.13 went to programs. The full breakdown, from its IRS Form 990:
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All science & technology charities · Largest charities in Washington
Questions people ask
How much of Institute for Systems Biology's spending goes to programs?
In calendar year 2024, Institute for Systems Biology reported that 71.1% of its $47.6 million in expenses went to program services, 28.0% to management and general and 0.9% to fundraising (Form 990, Part IX).
How much does Institute for Systems Biology pay its top executive?
The largest total compensation Institute for Systems Biology reported for one person in calendar year 2024 was $3,178,068, for the role of DIRECTOR - THRU 3/24 (Form 990, Part VII, including compensation from related organizations and other compensation).
Where does Institute for Systems Biology get its money?
Of $42.3 million in revenue in calendar year 2024, 89.6% came from contributions and grants (including 55.3% from government grants) and 1.9% from program service revenue (Form 990, Part VIII).
Is Institute for Systems Biology a registered charity?
The IRS lists EIN 91-2003593 as a 501(c)(3) organization (publicly supported organization (170(b)(1)(a)(vi))), and its records show contributions as tax-deductible. Form 990 filings on record here cover tax years 2019, 2020, 2021, 2022, 2023, 2024. A filing shows what the organization reported; it doesn't by itself show whether a program works.
Sources
- 2024: Form 990 for calendar year 2024, object 202513099349301866 · read the filing · XML
- 2023: Form 990 for calendar year 2023, object 202443169349306404 · read the filing
- 2022: Form 990 for calendar year 2022, object 202343179349312159 · read the filing
- 2021: Form 990 for calendar year 2021, object 202203129349302655 · read the filing
- 2020: Form 990 for calendar year 2020, object 202113189349300961 · read the filing
- 2019: Form 990 for calendar year 2019, object 202003149349304180 · read the filing
All filings for EIN 91-2003593: ProPublica Nonprofit Explorer · IRS Tax Exempt Organization Search. Figures are as the organization reported them; we have not audited them.