Charity Impact Media

Home › Medical research

Clayton Foundation For Research

Houston, TX · EIN 74-1541767 · 501(c)(3) · Hospital or medical research organization
Latest filing: Form 990 for calendar year 2024 (tax year 2024) · View the filing · Correct or respond

Clayton Foundation For Research reported $14.9 million in revenue and $10.9 million in expenses for calendar year 2024. Of every $100 it spent, $82.94 went to program services, $17.06 to management and general costs and $0.00 to fundraising. Its largest source of revenue was investment income: 85.7% of the total. The highest compensation it reported for one person was $785,428 (Trustee). 8 people received more than $100,000 in reportable compensation. Revenue rose 42% between 2020 and 2024. Source: Form 990, 2024.

Where $100 of spending went

Calendar year 2024 · Form 990, Part IX, line 25 · total expenses $11M

For context, the median across 169 covered medical research charities: $87.02 programs, $12.87 management, $0.11 fundraising (medians computed separately, so they may not sum to $100).

Where $100 of revenue came from

Calendar year 2024 · Form 990, Part VIII · total revenue $15M

The 990 scorecard · same measures for every charity, no grades

2024 filing. Median across 169 covered charities in this category, from their latest filings.
Measure2024Median
Program services
Part IX 25(B) ÷ 25(A)
82.9%83.9%
Management & general
Part IX 25(C) ÷ 25(A)
17.1%12.4%
Fundraising
Part IX 25(D) ÷ 25(A)
0.0%0.1%
Fundraising cost per $1 of contributions
Part IX 25(D) ÷ Part VIII 1h
$0.00$0.01
Contributions & grants share of revenue
Part VIII 1h ÷ 12
13.6%72.7%
Government grants share of revenue
Part VIII 1e ÷ 12
0.0%0.0%
Program service revenue share
Part VIII 2g ÷ 12
0.0%5.8%
Highest reported compensation
Part VII-A, columns D–F
$785,428$628,890
Highest compensation as share of expenses
Part VII-A ÷ Part IX 25(A)
7.18%1.94%
People paid over $100,000
Part VII, line 2
818
Net assets, in months of expenses
Part X 33(B) ÷ monthly expenses
151.113.3
Independent voting board members
Part VI 1a–1b
0 of 593.8%

A median is context, not a target: hospitals, universities, food banks and grantmakers spend in very different ways. What these measures can and can't tell you.

What the money paid for, in its own words

2024 · Form 990, Part III · the three largest programs by expense
$1.0M expenses · 11.4% of program spending

A long standing research project at the University of Texas at Austin under the direction of Dr. Brent Iverson is in the field of engineering proteases. One aim of the project is to discover engineered proteases that will serve as more efficient, next generation antibody replacements. The engineered proteases will cleave the protein disease target in a catalytic fashion, thus requiring much less drug and enabling far lower doses and potentially fewer side effects. This project has resulted in the generation of a technology platform to support the development of protease therapeutics called…

$965K expenses · 10.6% of program spending

A research project at Baylor College of Medicine in gene and protein therapy focuses on inappropriate cell division and cell death within the human body. Much of the work is devoted to intraocular angiogenesis, with particular attention to: (1) the signals that control this process, (2) the development of animal models of human ocular disease, and (3) development of potential therapies. New targets have been identified and potential therapeutic agents are being developed and tested for the treatment of wet AMD, Diabetic Retinopathy, and Retinopathy of Prematurity

$910K expenses · 10.0% of program spending

The conduct of a longstanding research program at the University of Texas M. D. Anderson Cancer Center(which program moved to Texas A&M Institute of Biosciences and and Technology during the year) , the purpose of which is to design and develop novel targeted therapeutic agents that target a powerful human toxin to specifically destroy cancer cells for the treatment of numerous cancer targets and other disease indications. A number of collaborations have been undertaken with researchers at various institutions (e.g., University of California San Diego). Patent applications have been filed by…

$6.2M all other programs (line 4d)

Highest reported compensation

2024 · Form 990, Part VII, Section A · roles as filed; names are in the filing, not here
RoleFrom this orgFrom related orgsOtherTotal
Trustee
Director/trustee, 8.00 hrs/week
$100,624$585,391$99,413$785,428
Trustee, President, Treasurer
Director/trustee, officer, 20.00 hrs/week
$283,402$402,613$99,413$785,428
Trustee, Vice President
Director/trustee, officer, 20.00 hrs/week
$210,286$475,729$99,413$785,428
Trustee VP, Secretary
Director/trustee, officer, 4.00 hrs/week
$159,140$458,605$89,294$707,039
Trustee, Chairman
Director/trustee, officer, 5.00 hrs/week
$100,624$256,424$49,850$406,898
VP, Assistant Treasurer
Officer, 40.00 hrs/week
$222,000$0$83,150$305,150
Assistant Secretary
Officer, 40.00 hrs/week
$178,200$0$76,580$254,780
Project Researcher
Listed in Part VII, 40.00 hrs/week
$114,406$0$40,030$154,436

8 people received more than $100,000 in reportable compensation from Clayton Foundation For Research (Part VII, line 2). Compensation of current officers, directors and key employees totaled $1.7M (Part IX, line 5).

5 years of filings

Form 990, Parts I, VII, IX and X · each row is that year's own filing, linked
RevenueExpenses
$0$5.0M$10M$15M$20M20202021202220232024$15M$11M
FilingRevenueExpensesProgramsNet assetsTop pay
2024 ⓘ$15M$11M82.9%$138M$785,428
2023 ⓘ$11M$11M87.5%$123M$761,256
2022 ⓘ$6.6M$10M85.7%$106M$716,492
2021 ⓘ$11M$10M85.5%$139M$673,008
2020 ⓘ$10M$9.2M85.1%$116M$660,426

Governance answers, as filed

2024 · the organization's own yes/no answers; explanations, if any, are in Schedule O of the filing · what each means
  • Voting board members, and how many are independent Part VI, lines 1a–1b5 · 0 independent
  • Audited financial statements Part XII 2bYes
  • Conflict-of-interest policy Part VI 12aYes
  • Whistleblower policy Part VI 13Yes
  • Document retention policy Part VI 14Yes
  • Independent process for top executive pay Part VI 15aYes
  • Board given the 990 before filing Part VI 11aYes
  • Family or business ties among insiders Part VI 2Yes
  • Aware of a significant diversion of assets Part VI 5No
  • Excess benefit transaction with an insider Part IV 25aNo
  • Loans to or from insiders outstanding Part IV 26No
  • Lobbying, or a 501(h) election in effect Part IV 4No
  • Over $15,000 of professional fundraising services Part IV 18No
  • Over $10,000 of activity outside the U.S. Part IV 14bYes
  • Employees Part I, line 553

Largest outside contractors

2024 · Form 990, Part VII, Section B · businesses only
Brorby Crozier & Dobie PC
Legal
$578,723

Individuals listed as contractors are left out. 1 contractors were paid more than $100,000 in all.

Correct a figure or respond

Every number above is copied from Clayton Foundation For Research's own Form 990. If one doesn't match the filing, that's our error and we'll fix it. If you work for Clayton Foundation For Research, you can publish a response that is linked from this page.

Similar-sized charities in this cause

All medical research charities · Largest charities in Texas

Questions people ask

How much of Clayton Foundation For Research's spending goes to programs?

In calendar year 2024, Clayton Foundation For Research reported that 82.9% of its $10.9 million in expenses went to program services, 17.1% to management and general and 0.0% to fundraising (Form 990, Part IX).

How much does Clayton Foundation For Research pay its top executive?

The largest total compensation Clayton Foundation For Research reported for one person in calendar year 2024 was $785,428, for the role of Trustee (Form 990, Part VII, including compensation from related organizations and other compensation).

Where does Clayton Foundation For Research get its money?

Of $14.9 million in revenue in calendar year 2024, 13.6% came from contributions and grants and 0.0% from program service revenue (Form 990, Part VIII).

Is Clayton Foundation For Research a registered charity?

The IRS lists EIN 74-1541767 as a 501(c)(3) organization (hospital or medical research organization), and its records show contributions as tax-deductible. Form 990 filings on record here cover tax years 2020, 2021, 2022, 2023, 2024. A filing shows what the organization reported; it doesn't by itself show whether a program works.

Sources

  • 2024: Form 990 for calendar year 2024, object 202523219349307322 · read the filing · XML
  • 2023: Form 990 for calendar year 2023, object 202443199349310679 · read the filing
  • 2022: Form 990 for calendar year 2022, object 202303199349308125 · read the filing
  • 2021: Form 990 for calendar year 2021, object 202223189349313432 · read the filing
  • 2020: Form 990 for calendar year 2020, object 202123199349321002 · read the filing

All filings for EIN 74-1541767: ProPublica Nonprofit Explorer · IRS Tax Exempt Organization Search. Figures are as the organization reported them; we have not audited them.