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Largest charities in South Carolina

200 of 248 covered charities based in South Carolina, by contributions and grants on their latest IRS Form 990.

CharityContributionsRevenueProgramsFundraisingTop pay
The Blackbaud Giving Fund
Charleston, SC · 2025
$544M$546M99.8%0.0%$365K
The Charter Institute at Erskine
Columbia, SC · FY2025
$294M$300M80.0%0.0%$333K
Prisma Health-Midlands
Greenville, SC · FY2025
$151M$2.08B89.3%0.0%$3.4M
Medical University of South Carolina Foundation
Charleston, SC · FY2025
$93M$137M81.5%9.7%$635K
Welvista
Columbia, SC · FY2025
$92M$96M97.4%0.5%$294K
Lowcountry Food Bank
Charleston, SC · 2024
$84M$90M96.0%1.8%$285K
Clemson University Foundation
Clemson, SC · FY2025
$84M$119M77.5%10.3%$919K
South Carolina First Steps to
Columbia, SC · FY2025
$72M$72M96.3%0.1%$123K
The Gamecock Club
Columbia, SC · FY2025
$55M$56M85.2%6.5%$247K
University of South Carolina Educational Foundation
Columbia, SC · FY2025
$54M$85M91.0%2.4%$593K
The Heron Institute
Greenville, SC · FY2025
$50M$50M83.9%0.0%$245K
Harvest Hope Food Bank
Columbia, SC · FY2024
$49M$50M97.4%1.1%$208K
Prisma Health
Greenville, SC · FY2025
$43M$340M83.4%0.0%$3.4M
Water Missions International
North Charleston, SC · FY2025
$42M$42M87.9%6.7%$258K
National Wild Turkey Federation
Edgefield, SC · FY2025
$41M$54M84.3%2.9%$441K
Goodwill Industries of Upstatemidlands South Carolina
Greenville, SC · FY2025
$38M$62M93.1%0.4%$550K
Furman University
Greenville, SC · FY2025
$38M$297M89.4%1.9%$828K
Central Carolina Community Foundation
Columbia, SC · FY2025
$37M$47M93.8%3.7%$201K
Spartanburg County Foundation
Spartanburg, SC · 2025
$37M$51M91.3%1.1%$263K
Gleamns Human Resources Commission
Greenwood, SC · FY2025
$37M$37M91.0%0.0%$146K
Richland County Public Library
Columbia, SC · FY2025
$36M$37M90.8%1.5%$240K
Greenville Renewable Energy Education Network
Greenville, SC · FY2025
$35M$36M79.6%0.0%$200K
Sunbelt Human Advancement Resources
Greenville, SC · FY2025
$34M$34M94.9%0.0%$227K
Meeting Street Schools
Charleston, SC · FY2025
$34M$47M96.3%0.1%$327K
Community Foundation of Greenville
Greenville, SC · 2024
$31M$38M93.4%0.5%$312K
Wateree Community Actions
Columbia, SC · 2024
$29M$29M94.3%0.0%—
The Citadel Foundation
Charleston, SC · 2024
$27M$38M69.1%19.5%$610K
Anderson University
Anderson, SC · FY2025
$26M$177M89.2%1.4%$955K
Insurance Institute for Business & Home Safety
Richburg, SC · 2025
$26M$30M74.6%0.0%$1.0M
James Island Charter High School
Charleston, SC · FY2025
$26M$28M85.4%0.0%$167K
Charleston School of Law
Charleston, SC · 2024
$25M$27M67.9%2.8%$12,500
Claflin University
Orangeburg, SC · FY2025
$25M$69M61.4%1.9%$1.1M
Voorhees College
Denmark, SC · FY2025
$25M$37M65.9%0.0%$188K
Radio Training Network
Greenville, SC · 2024
$25M$36M84.6%4.4%$506K
Miracle Hill Ministries
Greenville, SC · FY2025
$24M$26M82.9%8.1%$175K
Coastal Community Foundation of South Carolina
N Charleston, SC · 2024
$24M$46M82.0%2.5%$401K
American Leadership Academy South Carolina
Lexington, SC · FY2025
$24M$25M69.5%0.0%$109K
Palmetto Goodwill
North Charleston, SC · 2024
$24M$65M88.1%0.3%$543K
South Carolina Virtual Charter School
West Columbia, SC · FY2025
$23M$25M85.6%0.0%$159K
Legacy Early College
Greenville, SC · FY2025
$23M$24M81.6%0.0%$234K
Berkeley Charter Education Association I
Goose Creek, SC · FY2025
$23M$24M71.8%0.0%—
Benedict College
Columbia, SC · FY2024
$22M$53M61.9%1.4%$602K
College of Charleston Foundation
Charleston, SC · FY2025
$22M$23M64.1%28.7%$825K
St Lukes Free Medical Clinic of Spartanburg
Spartanburg, SC · 2025
$21M$21M99.0%0.3%$103K
Children's Trust of South Carolina
Columbia, SC · FY2025
$21M$21M91.4%1.2%$227K
York Preparatory Academy
Rock Hill, SC · FY2025
$21M$23M72.6%0.0%$231K
Roper Hospital
Charleston, SC · 2024
$21M$539M86.2%0.0%$2.5M
South Carolina Education Futures
Columbia, SC · FY2025
$20M$20M79.1%0.0%$146K
Eau Claire Cooperative Health Center
Columbia, SC · 2024
$19M$77M76.7%0.0%$480K
Pee Dee Community Action Partnership
Florence, SC · 2024
$19M$19M95.0%0.0%—
Anmed Health
Anderson, SC · 2024
$18M$855M91.2%0.0%$2.1M
Bridges Preparatory School
Beaufort, SC · FY2025
$17M$19M69.8%0.0%$202K
Horse Creek Academy
Aiken, SC · FY2025
$17M$18M77.3%0.0%$197K
Greenwood Genetic Center
Greenwood, SC · FY2025
$17M$31M81.4%1.1%$463K
Wofford College
Spartanburg, SC · FY2025
$17M$166M89.9%1.8%$810K
Waccamaw Economic Opportunity
Conway, SC · 2024
$17M$17M93.1%0.0%$156K
Orange Grove Charter School
Charleston, SC · FY2025
$16M$19M85.9%0.0%$203K
High Point Academy
Spartanburg, SC · FY2025
$16M$17M62.5%0.0%$141K
ROAD2HIRE
Fort Mill, SC · 2024
$16M$17M86.9%0.0%—
One-Eighty Place
Charleston, SC · FY2025
$16M$18M94.6%2.6%$268K
The Inspirational Network
Indian Land, SC · 2024
$16M$35M65.9%7.3%$5.0M
Community Foundation of the Lowcountry
Hilton Head Island, SC · FY2025
$15M$19M89.8%1.3%$295K
Caresouth Carolina
Hartsville, SC · FY2025
$15M$86M73.0%0.0%$580K
American Leprosy Missions
Greenville, SC · FY2025
$15M$16M75.1%18.3%$253K
United States Endowment for Forestry
Greenville, SC · 2024
$15M$10M94.1%0.0%$522K
McLeod Health Foundation
Florence, SC · FY2025
$15M$17M80.6%11.4%$283K
OCAB Community Action Agency
Orangeburg, SC · 2024
$14M$14M85.8%0.0%$204K
Spartanburg Academic Movement
Spartanburg, SC · 2024
$14M$14M95.1%1.8%$177K
Building Equity Sooner for Tomorrow
Greenville, SC · FY2025
$14M$14M100.0%0.0%$271K
South Carolina Legal Services
Greenville, SC · 2025
$13M$13M90.4%0.4%$212K
Eastern Carolina Homelessness Org
Myrtle Beach, SC · 2024
$13M$14M95.6%0.0%$216K
Little River Medical Center
Little River, SC · FY2025
$13M$50M84.8%0.0%$427K
United Way of the Midlands
Columbia, SC · FY2025
$13M$14M80.1%13.6%$314K
National Wild Turkey Federation Endowment Foundation
Edgefield, SC · FY2024
$13M$14M100.0%0.0%—
Liberty Steam Charter School
Sumter, SC · FY2025
$12M$13M84.5%0.0%$200K
Claflin Qalicb
Orangeburg, SC · 2024
$12M$13M87.5%0.0%$193K
Converse University
Spartanburg, SC · FY2025
$12M$51M84.3%3.9%$314K
Beaufort-Jasper-Hampton Comprehensive Health Services
Okatie, SC · FY2024
$12M$33M72.8%0.0%$356K
South Carolina Christian Foundation
Spartanburg, SC · 2024
$12M$18M95.6%0.9%$124K
United Way of Greenville County
Greenville, SC · 2024
$12M$12M73.2%19.1%$404K
Hopehealth
Florence, SC · 2024
$12M$200M83.0%0.0%$458K
Christ Church Episcopal School
Greenville, SC · FY2025
$12M$44M77.7%4.7%$448K
Advanced Technology International Foundation
Summerville, SC · FY2025
$12M$12M94.4%0.2%$740K
Carolina Community Actions
Rock Hill, SC · FY2025
$12M$12M92.1%0.0%$179K
Beaufort-Jasper Eoc
Beaufort, SC · 2024
$12M$12M91.8%0.0%—
Roper St Francis Foundation
Charleston, SC · 2024
$12M$16M46.8%24.3%$980K
Safe Harbor
Greenville, SC · 2024
$12M$13M71.4%9.7%$139K
Lowcountry Land Trust
Charleston, SC · FY2025
$11M$13M91.8%5.1%$161K
Charleston County Human Services Commission
Charleston, SC · 2024
$11M$12M88.4%0.0%—
Riverview Charter School
Beaufort, SC · FY2025
$11M$12M87.1%0.0%$59,191
Chanticleer Athletic Foundation
Conway, SC · FY2025
$11M$13M84.3%4.0%$122K
Horry County Disabilities & Special Needs Board
Conway, SC · FY2025
$11M$13M81.2%0.0%$125K
South Carolina Acceleration Academies
North Charleston, SC · FY2025
$11M$11M48.4%0.0%—
Morris College
Sumter, SC · FY2025
$11M$21M62.5%0.1%$160K
ETV Endowment of South Carolina
Spartanburg, SC · FY2025
$11M$15M85.7%6.9%$309K
Ronald McDonald House Charities of Charleston South Carolina
Charleston, SC · 2025
$11M$12M64.2%29.2%$111K
Gray Collegiate Academy
West Columbia, SC · FY2025
$11M$12M81.1%0.0%$325K
Charleston Charter School for Math and Science
Charleston, SC · FY2025
$11M$11M79.0%0.0%$147K
Royal Live Oaks Academy - Ridgeland
Hardeevile, SC · FY2025
$10M$11M80.2%0.0%$213K
Greater Lake City Alliance
Lake City, SC · 2024
$10M$14M93.1%0.0%$185K
Virtus Academy of South Carolina
Florence, SC · FY2025
$10M$10M66.0%0.0%$85,715
Prisma Health-Upstate
Greenville, SC · FY2025
$10.0M$3.61B89.7%0.0%$3.4M
Columbia International University
Columbia, SC · FY2025
$10.0M$71M78.2%3.0%$391K
Charleston Animal Society
North Charleston, SC · 2025
$10.0M$14M82.4%13.8%$281K
Mainsail Health Partners
Charleston, SC · FY2025
$9.8M$15M87.1%0.0%$1.2M
Lexington Richland Alcohol & Drug Abuse Council
Columbia, SC · FY2025
$9.7M$12M80.4%0.0%$200K
Family Health Centers
Orangeburg, SC · 2025
$9.6M$18M78.7%0.0%$282K
Riverwalk Academy
Rock Hill, SC · FY2025
$9.5M$10M84.2%0.0%$192K
McLeod Regional Medical Center of the Pee Dee
Florence, SC · FY2025
$9.4M$1.49B87.3%0.0%$2.4M
Aikenbarnwell Co Caa
Aiken, SC · FY2025
$9.4M$11M96.7%0.0%$165K
Connie Maxwell Children's Ministries
Greenwood, SC · FY2025
$9.3M$23M72.0%14.4%$266K
Fetter Health CARE Network
Charleston, SC · FY2025
$9.1M$24M79.2%0.0%$323K
Spartanburg Regional Healthcare System Foundation
Spartanburg, SC · FY2025
$9.0M$13M73.4%12.1%$432K
South Carolina Research Authority
Columbia, SC · FY2023
$8.6M$16M82.4%0.0%$353K
Brookgreen Gardens
Pawleys Island, SC · FY2025
$8.6M$18M81.1%13.8%$353K
Prisma Health Midlands Foundation
Columbia, SC · FY2025
$8.6M$12M87.2%8.3%$270K
Bon Secours-St Francis Xavier Hospital
Charleston, SC · 2024
$8.5M$621M90.4%0.0%$2.5M
Allen University
Columbia, SC · FY2025
$8.4M$23M70.4%1.3%$425K
New Horizon Family Health Services
Greenville, SC · FY2025
$8.3M$31M76.4%0.0%$282K
Sandhills Medical Foundation
McBee, SC · FY2025
$8.3M$35M88.4%0.0%$372K
Erskine College and Theological Seminary
Due West, SC · FY2025
$8.0M$48M84.3%1.1%$227K
Ashley Hall Foundation
Charleston, SC · FY2025
$7.4M$32M81.2%3.0%$487K
Carolina Health Centers
Greenwood, SC · FY2025
$7.4M$40M74.5%0.0%$303K
Thornwell
Clinton, SC · 2024
$7.2M$14M77.6%11.4%$283K
AID Upstate
Greenville, SC · 2024
$7.1M$12M96.0%0.2%$263K
Epworth Children's Home
Columbia, SC · 2025
$7.0M$22M81.7%5.0%$251K
Low Country Health CARE System
Fairfax, SC · FY2025
$6.9M$32M77.3%0.0%$271K
Affinity Health Center
Rock Hill, SC · 2024
$6.8M$28M94.4%0.0%$251K
Presbyterian College
Clinton, SC · FY2025
$6.5M$77M90.3%1.6%$354K
Spoleto Festival USA
Charleston, SC · FY2025
$6.2M$11M73.2%8.4%$288K
Southern Wesleyan University
Central, SC · FY2025
$6.1M$31M81.5%2.9%$239K
Columbia College
Columbia, SC · FY2025
$6.0M$38M76.3%2.8%$409K
University of South Carolina Business Partnership Foundation
Columbia, SC · FY2025
$6.0M$17M92.3%0.0%$227K
Rural Health Services
Aiken, SC · FY2025
$5.8M$21M78.8%0.0%$438K
Roper St Francis Mt Pleasant Hospital
Mount Pleasant, SC · 2024
$5.7M$140M86.8%0.0%$2.5M
Bju
Greenville, SC · FY2025
$5.7M$115M82.9%0.7%$184K
North Greenville University
Tigerville, SC · FY2025
$5.5M$72M89.6%1.7%$417K
Regenesis Health CARE
Spartanburg, SC · FY2025
$5.4M$38M75.9%0.0%$352K
Charleston Southern University
Charleston, SC · FY2025
$5.3M$125M91.6%1.2%$444K
South Carolina Aquarium
Charleston, SC · 2024
$5.2M$20M75.3%9.4%$390K
YMCA of Greenville
Greenville, SC · 2024
$4.9M$30M73.7%2.7%$324K
Coker University
Hartsville, SC · FY2025
$4.9M$29M69.6%3.0%$390K
Spartanburg Methodist College
Spartanburg, SC · FY2025
$4.8M$31M79.2%1.6%$283K
Bishop Gadsden Episcopal Retirement Community
Charleston, SC · 2025
$4.6M$83M84.6%0.6%$481K
Newberry College
Newberry, SC · FY2025
$4.6M$66M91.1%1.7%$264K
Peace Center Foundation
Greenville, SC · FY2025
$4.5M$42M90.8%3.6%$852K
Lowcountry AIDS Services Childs
Charleston, SC · 2024
$4.4M$14M91.6%2.0%$209K
Community Medicine Foundation
Rock Hill, SC · FY2025
$4.4M$18M66.7%0.0%$315K
Tandem Health Sc
Sumter, SC · FY2025
$4.0M$34M77.8%0.0%$353K
Hampton Regional Medical Center
Varnville, SC · FY2025
$4.0M$41M84.6%0.0%$614K
Health CARE Partners of South Carolina
Conway, SC · FY2026
$4.0M$26M76.1%0.0%$371K
The Charles Lea Center
Spartanburg, SC · FY2024
$4.0M$37M86.1%0.0%$229K
Kershawhealth
Camden, SC · FY2025
$3.9M$25M91.0%0.0%$210K
Project Hope Foundation
Greenville, SC · FY2025
$3.3M$22M89.5%5.6%$132K
Charleston Gaillard Management Corporation
Charleston, SC · FY2025
$3.3M$12M87.4%5.4%$431K
Heritage Classic Foundation
Hilton Head Island, SC · 2024
$3.2M$19M98.4%0.0%$310K
Careteam Plus
Conway, SC · FY2025
$3.1M$23M97.5%0.1%$286K
Wilds Christian Association
Taylors, SC · FY2025
$3.0M$10M77.6%3.8%$126K
Oconee Medical Holdings
Seneca, SC · FY2025
$2.8M$2.6M98.8%0.0%—
Roper St Francis Healthcare
Ladson, SC · 2024
$2.7M$259M81.4%0.0%$2.5M
Roper St Francis Physicians Network
Ladson, SC · 2024
$2.3M$213M81.3%0.0%$2.5M
St Francis Hospital
Greenville, SC · 2024
$2.2M$851M94.5%0.0%$2.0M
Spartanburg Day School
Spartanburg, SC · FY2025
$2.1M$18M72.2%3.2%$562K
United Housing Connections
Greenville, SC · FY2025
$2.0M$5.6M89.5%0.4%$145K
Hospice of the Upstate
Anderson, SC · 2025
$2.0M$15M85.7%1.9%$273K
Lutheran Homes of South Carolina
Irmo, SC · FY2025
$1.9M$95M89.1%0.0%$704K
St Joseph's Catholic School
Greenville, SC · FY2025
$1.8M$15M85.6%4.8%$348K
Senior Solutions
Anderson, SC · FY2025
$1.7M$11M84.9%1.7%$96,319
McLeod Health
Florence, SC · FY2025
$1.6M$400M89.5%0.0%$2.4M
Hilton Head Christian Academy
Bluffton, SC · FY2025
$1.6M$14M89.6%2.3%$265K
Wesley Commons
Greenwood, SC · FY2025
$1.6M$30M73.8%0.9%$650K
Roper St Francis Hospital - Berkeley
Summerville, SC · 2024
$1.5M$152M86.0%0.0%$2.5M
Limestone University
Gaffney, SC · FY2025
$1.5M$47M75.6%0.8%$257K
Hammond School
Columbia, SC · FY2025
$1.5M$27M89.3%0.0%$430K
York County Board of Disabilities and Special Needs
York, SC · FY2025
$1.4M$20M86.9%0.0%$217K
South Carolina Youth Advocate Program
Columbia, SC · 2025
$1.3M$27M75.3%0.0%$754K
Scbma
Columbia, SC · FY2025
$1.3M$32M88.9%0.7%$299K
Southside Christian School of the Upstate
Simpsonville, SC · FY2025
$1.2M$24M84.2%3.0%$282K
Leroy Springs & Company
Fort Mill, SC · 2024
$1.2M$24M85.7%2.3%$314K
The Camp Cole Foundation
Eastover, SC · 2025
$1.1M$2.3M86.4%4.5%$115K
National Association of Competitive Socc Soccer Clubs D/B/A US Club Soccer
Mt Pleasant, SC · FY2025
$1.1M$22M87.3%1.2%$239K
Hilton Head Preparatory School
Hilton Head Lsland, SC · FY2025
$1.0M$13M92.0%3.5%$273K
Conway Hospital
Conway, SC · FY2025
$1.0M$417M84.8%0.0%$1.1M
Young Mens Christian Association of Greater Spartanburg
Spartanburg, SC · 2025
$897K$10M82.1%4.4%$190K
Berkeley Citizens
Moncks Corner, SC · FY2025
$894K$17M96.8%0.1%$215K
National Wild Turkey Federation
Edgefield, SC · FY2025
$863K$16M100.0%0.0%—
Upper Palmetto YMCA
Rock Hill, SC · 2025
$848K$24M90.8%0.7%$314K
South Carolina Episcopal Home at Still Hopes
W Columbia, SC · FY2025
$799K$48M85.7%0.5%$771K
Georgetown Memorial Hospital
Georgetown, SC · FY2025
$776K$268M79.5%0.0%$1.2M
The Young Men's Christian Assoc of Columbia SC
Lexington, SC · 2025
$750K$10M88.7%1.4%$190K
Heathwood Hall Episcopal School
Columbia, SC · FY2025
$737K$29M77.5%0.4%$461K
Wilson Hall
Sumter, SC · FY2025
$706K$10M84.3%0.2%$186K
Babcock Center
West Columbia, SC · FY2025
$633K$43M90.0%0.0%$224K
Pinewood Preparatory School
Summerville, SC · FY2025
$605K$12M76.5%7.3%$407K
Rolling Green Village
Greenville, SC · 2024
$589K$29M63.7%0.0%$144K
Sherman College of Straight Chiropractic
Spartanburg, SC · 2025
$471K$17M76.5%3.9%$415K
McLeod Medical Center Dillon
Florence, SC · FY2025
$455K$88M95.0%0.0%$2.4M
Presbyterian Communities of South Carolina
Columbia, SC · 2025
$407K$88M72.4%0.5%$426K
Tri-Development Center of Aiken County
Aiken, SC · FY2025
$383K$23M89.9%0.0%$139K
McLeod Health Clarendon
Florence, SC · FY2025
$353K$103M97.2%0.0%$2.4M